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Generic Vesicare

Vesicare photo

Generic Vesicare (Solifenacin)

Urinary Tract

Generic Vesicare reduces muscle spasms of the bladder and urinary tract. Generic Vesicare is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage).

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Solifenacin tablet

What is this medicine?

SOLIFENACIN reduces muscle spasms of the bladder and urinary tract.

Solifenacin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage).

What should I tell my health care provider before I take this medicine?

You should not use Solifenacin if you are allergic to solifenacin, or have certain conditions. Be sure your doctor knows if you have:

  • untreated or uncontrolled narrow-angle glaucoma;
  • a stomach disorder causing delayed emptying; or
  • if you are unable to urinate.

To make sure you can safely take Solifenacin, tell your doctor if you have any of these other conditions:

  • glaucoma;
  • liver disease;
  • kidney disease;
  • a blockage in your stomach or intestines; or
  • a history of Long QT syndrome.
  • FDA pregnancy category C. It is not known whether Solifenacin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether solifenacin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using Solifenacin.

How should I take this medicine?

Take Solifenacin exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Solifenacin is usually taken once per day. Follow your doctor's instructions.

Take this medicine with water.

Do not crush, chew, or break the tablet. Swallow it whole.

Solifenacin can be taken with or without food.

Store Solifenacin at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What should I watch for while taking this medicine?

Avoid becoming overheated or dehydrated during exercise and in hot weather. Solifenacin can decrease perspiration and you may be more prone to heat stroke.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

What side effects may I notice from this medicine?

Get emergency medical help if you have any of these signs of an allergic reaction to Solifenacin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using Solifenacin and call your doctor at once if you have a serious side effect such as:

  • hot, dry skin and extreme thirst;
  • severe stomach pain, or constipation for 3 days or longer;
  • pain or burning when you urinate;
  • vision changes, eye pain, or seeing halos around lights;
  • urinating less than usual or not at all;
  • confusion, hallucinations;
  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling); or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious Solifenacin side effects may include:

  • headache, dizziness, drowsiness, feeling tired;
  • dry mouth, hoarse voice;
  • dry eyes, blurred vision;
  • nausea, loss of appetite, upset stomach, heartburn;
  • mild constipation; or
  • fever, sore throat, body aches, or other flu symptoms.

What may interact with this medicine?

Tell your doctor about all other medicines you use, especially:

  • arsenic trioxide (Trisenox);
  • carbamazepine (Carbatrol, Equetro, Tegretol);
  • conivaptan (Vaprisol);
  • nefazodone;
  • phenytoin (Dilantin);
  • tacrolimus (Prograf);
  • vandetanib (Caprelsa);
  • antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), or voriconazole (Vfend);
  • the hepatitis C medications boceprevir (Victrelis) or telaprevir (Incivek);
  • HIV/AIDS medicine such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, Kaletra), or saquinavir (Invirase);
  • an antibiotic such as azithromycin (Zithromax, Zmax, Z-Pack), clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), moxifloxacin (Avelox), pentamidine (NebuPent, Pentam), rifampin (Rifadin, Rifater, Rifamate), or telithromycin (Ketek);
  • an antidepressant such as amitriptylline (Elavil, Vanatrip, Limbitrol), citalopram (Celexa), clomipramine (Anafranil), or desipramine (Norpramin);
  • anti-malaria medications such as chloroquine (Aralen), halofantrine (Halfan), or mefloquine (Lariam);
  • heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), dronedarone (Multaq), flecainide (Tambocor), ibutilide (Corvert), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quin-G), or sotalol (Betapace);
  • medicine to prevent or treat nausea and vomiting such as dolasetron (Anzemet), droperidol (Inapsine), or ondansetron (Zofran);
  • medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), mesoridazine (Serentil), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);
  • migraine headache medicine such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig); or
  • narcotic medication such as methadone (Methadose, Diskets, Dolophine).

This list is not complete and other drugs may interact with Solifenacin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I keep my medicine?

Store at room temperature away from moisture and heat.

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